Nonregenerative Anemia in Dogs and Cats
نویسنده
چکیده
Causes of nonregenerative anemia may be categorized by a mnemonic using the letter D: Detection, Delay, Destruction, Deficiency, Deep-Development-Dam, Diversion, Displacement, Depression, Dilution and Drugs. The categories are not mutually exclusive and anemia may be multifactorial in etiology. A pathophysiologic mechanism common to many of the causes is defective development of erythroid cells in the BM, which is reflected in a BM (BM) biopsy quantitatively as altered absolute and relative numbers of developing RBCs, and qualitatively as altered appearance of these cells (dysplasia). Cats with chronic anemia may develop reversible cardiomegaly and heart failure, multifocal retinal bleeding, and pica.
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